The World Drug Report presents a comprehensive overview of the latest developments in drug markets. It covers production;; trafficking;; consumption and related health consequences. Chapter 1 of this year’s report examines the global situation and the latest trends in the different drug markets and the extent of illicit drug use;; as well as the related health impact. Chapter 2 addresses the phenomenon of new psychoactive substances (NPS);; which can have deadly consequences for their users but are hard to control;; with dynamic;; fastmutating producers and “product lines” which have emerged over the past decade.