This social development bulletin, published by the Economic and Social Commission for Western Asia (ESCWA), highlights the challenges faced by persons with disabilities in humanitarian emergencies. The report explores the extent of inequality and exclusion faced by this demographic, as well as the state of implementation of the Convention on the Rights of Persons with Disabilities in the Arab region. The report concludes with recommendations to build resilience and protect the rights of people with disabilities, ensure the full and effective participation of persons with disabilities and their representative organizations in all phases of emergency management, adopt a twin-track approach in all phases of emergency management, improve the evidence base on disability, invest in disability-inclusive disaster risk reduction, apply universal design principles. Also included in this report is an interview with Dr. Ghassan Abu Sitta, the Chief of the Plastic and Reconstructive Surgery Division at the American University of Beirut Medical Center and a frequent volunteer in Palestine. Discussed is his experience in the emergency medical response field and the obstacles faced by persons with disabilities.