This new edition of the MED Report is intended as a tool to support debate in the context of Rome MED. In particular,the volume collects insights,analyses and policy recommendations from different perspectives and countries,with a view to shedding light on current dynamics and future developments in the Mediterranean region at the political,security and socio-economic level. In this spirit,the first part of the Report highlights opportunities to be seized and provides policy options to build a peter future for the region. The second part of the Report focuses on today’s major regional challenges and is structured along the four main pillars of Rome MED: shared security,shared prosperity,migration,and civil society & culture. This volume is the result of the fruitful cooperation among all MED Scientific Partners. It benefited from the renewed partnership of Bruegel,the Royal Institute of International Afairs (Chatham House),the Deutsche Gesellschaf für Auswärtige Politik (DGAP),the European Council of Foreign Relations (ECFR),the European University Institute (EUI),the Institut Français des Relations Internationales (IFRI),and the Think Tanks and Civil Societies Program (TTCSP) of the University of Pennsylvania. In addition,this year the scientific partnership was enlarged to include seven institutes from the southern shore of the Mediterranean: Al-Ahram Center for Political and Strategic Studies; Al Sharq Forum; Carnegie Middle East Center; Institut Tunisien des Etudes Stratégiques (ITES); Jordan Center for Strategic Studies (CSS); OCP Policy Center; Middle East Research Institute (MERI). This expanded collaboration has allowed to further enrich the content of the volume and provide new views and ideas.