This paper was commissioned by the Education for All Global Monitoring Report as background information to assist in drafting the 2010 report. Using a social exclusion concept framework, this paper identifies several causes of marginalization of people with disabilities in the context of the MENA region. Focusing on Lebanon, Syria and Jordan, the incidence, prevalence, causes and characteristics of people with disabilities are reported. The educational experiences of children and youth with disabilities from early childhood through secondary school are described. Findings from these experiences are used to recommended strategies to address exclusionary policies and practices in order to promote inclusion. Strategies focus on legislation and policies, as well as addressing cultural and structural barriers through specific interventions.